NanoDrop ND-1000 Spectrophotometer
Wavelength Range
220 to 750nm
Wavelength Accuracy
1 nm
Detector Type
2048-element linear silicon CCD array
- Measures 1 μl samples with high accuracy and reproducibility
- Utilizes 1mm and 0.2mm path lengths for a wide dynamic range
- Measures high-concentration samples without dilution, up to 50 times more concentrated than standard cuvette spectrophotometers
- Uses surface tension technology for sample containment and quick cleanup
- Suitable for various applications, including nucleic acid concentration, protein analysis, cell density measurements, and UV-Vis spectrophotometry
- Fully tested to perform at factory specifications before shipping

The NanoDrop ND-1000 is a full-spectrum spectrophotometer that measures 1 ul samples with high accuracy and reproducibility. The system uses 1mm and 0.2mm path lengths for each measurement cycle to provide an extensive dynamic range. The ND-1000 can measure high-concentration samples without dilution that many standard cuvette spectrophotometers cannot, measuring up to 50 times more concentrated solutions. Surface tension technology keeps the sample in place without the need for sample containment devices and allows for quick cleanup.
Applications include measuring: nucleic acid concentration and purity of nucleic acid samples up to 3700 nh/ul without dilution; fluorescent dye labeling density of nucleic acid microarray samples; purified protein analysis up to 100 mg/ml; expanded spectrum measurement and quantitation of fluorescent dye labeled proteins, conjugates, and metalloproteins; Bradford Assay analysis of protein; BCA Assay analysis of protein; Lowry Assay analysis of protein; cell density measurements; and general UV-Vis spectrophotometry.
All of our equipment is fully tested to perform at factory specifications before being shipped.
The NanoDrop ND-1000 Spectrophotometer includes:
- > Windows 10 Professional Data Station with Nanodrop Software
- > CF-1 Calibration Report
- > Power Cord
- > Full 180 Day Parts and Labor Warranty
NanoDrop ND-1000 Spectrophotometer Specifications
| Wavelength Range | 220 to 750 nm |
| Wavelength Accuracy | 1 nm |
| Wavelength Resolution | 3 nm (FWHM at Hg 546 nm) |
| Absorbance Range | 0.02 to 75 (10 mm equivalent absorbance) |
| Absorbance Precision | 0.003 absorbance (1mm path) |
| Detection Limit | 2 ng/microliter (dsDNA) |
| Spectral Resolution | 3 nm |
| Maximum Concentration | 3700 ng/microliter (dsDNA) |
| Sample Size | 1 microliter |
| Path Length | 1mm (with auto-ranging to 0.2 mm) |
| Light Source | Xenon flash lamp |
| Detector Type | 2048-element linear silicon CCD array |
| Measurement Cycle Time | 10 seconds |
| Dimensions | 5.5 x 7.9 in. (14 x 20 cm) |
| Weight | 3.5 lb. (1.6 kg) |
| Electrical Requirements | 12V DC, 6W |
- Confirm the power supply and PCB output correct, stable voltages across all required connections
- Inspect the display for any dim or dead pixels; replace affected components to maintain full visual clarity and operational accuracy
- Verify full functionality of all buttons, ensuring precise and responsive input control
- Check the XY assembly for proper movement and alignment; thoroughly clean all railings, removing any debris or contaminants
- Confirm stable software communication and connection between the instrument and PC, addressing any connectivity issues
- Inspect and clean or replace all filters as required to ensure optimal airflow and performance
- Examine internal wiring and electrical connections for any breaks, disconnections, or tears; replace or secure any compromised wiring
- Test the lamp’s full functionality, replacing it if any performance issues, dimming, or faults are detected
- Execute the necessary validation protocol, documenting completion with a date on a calibration/verification certificate
- Perform and verify appropriate updates to the PC operating system for compatibility and security
- Conduct a thorough cosmetic inspection, ensuring all external components meet quality and aesthetic standards
Technician Inspection and Recertification Checklist: Instruments
The Following Checklist Is to Be Performed on All Incoming and Outgoing Pieces of Equipment| Task | Completed? | Remarks? |
| Confirm stable, correct voltage outputs from power supply and PCB | Completed | |
| Inspect display for dim or dead pixels; replace as needed | Completed | |
| Verify functionality of all buttons for precise, responsive control | Completed | |
| Check XY assembly for proper movement; clean railings to remove debris | Completed | |
| Confirm stable software communication between instrument and PC | Completed | |
| Inspect and clean or replace filters to maintain optimal performance | Completed | |
| Examine internal wiring for damage; replace or secure compromised connections | Completed | |
| Test lamp functionality; replace if dimming or faults are detected | Completed | |
| Execute validation protocol and document on calibration/verification certificate | Completed | |
| Update PC operating system for compatibility and security | Completed | |
| Conduct cosmetic inspection to ensure quality of external components | Completed |
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