Agilent 6130A Single Quadrupole Mass Spectrometer w/ 1200 UPLC
Mass Range
2–3000 m/z
Mass Accuracy
± 0.13 u
Scan Speed
2500 u/s in standard mode, 5250 u/s in fast-scan mode
- Extended mass detection capability for analyzing a wide range of compounds
- High sensitivity performance supporting low-level detection in demanding applications
- Delivers unmatched analytical performance for routine QC and research applications
- Stable mass axis over extended operation for consistent, reliable results
- Flexible data acquisition with multiple modes selectable within a single run
- Support for both ESI and APCI ionization techniques for method versatility
- Positive ionization capability for a broad range of analytes
- Efficient scanning performance for both routine and fast analysis workflows
- Robust system stability designed for long-term analytical consistency
- Integrated data handling and acquisition flexibility for streamlined workflows
- Suitable for routine LC/MS applications requiring dependable qualitative and quantitative analysis

The Agilent 6130A Single Quadrupole Mass Spectrometer w/ 1200 UPLC is designed to deliver reliable, high-sensitivity mass analysis for routine and advanced laboratory applications. Offering an extended mass range from m/z 2 to 3000, the system provides the flexibility needed to analyze a wide variety of compounds, from small molecules to larger biomolecules. Its robust design ensures consistent mass accuracy and exceptional mass axis stability, supporting dependable results over extended analytical runs.
Engineered for efficiency, the 6130A features rapid scan speeds with both standard and fast-scan modes, enabling high-throughput workflows without sacrificing data quality. The system’s strong sensitivity in both scan and selected ion monitoring (SIM) modes allows for confident detection of low-level analytes, making it well-suited for trace analysis and quantitative applications. Additionally, the ability to cycle through multiple acquisition modes within a single run enhances method versatility and streamlines complex analyses.
With support for common ionization techniques such as ESI and APCI, the Agilent 6130A integrates seamlessly into a range of LC/MS workflows, providing dependable performance, operational flexibility, and the sensitivity required for modern analytical laboratories.
This Agilent MS system was recertified and calibrated by a factory trained engineer and is ready to ship on demand. This system comes with everything needed for easy installation and setup. All of our equipment is fully tested to perform at factory specifications before being shipped.
The Agilent 6130A Single Quadrupole Mass Spectrometer w/ 1200 UPLC includes:
- Agilent 6130A Single Quadrupole Mass Spectrometer
- Agilent MS40+ Rotary Vane Vacuum Pump
- G1948B ESI Ionization Source
- G1312B Binary Pump (G1311A Quaternary Pump available, please inquire)
- G1329A Autosampler
- G1330B ALS Thermostat
- G1316A TCC
- G1379B Degasser
- G1315C DAD Detector
- Windows 11 Professional 64-Bit Data Station with Flatscreen Monitor
- ChemStation Version 4.3 Software Installed
- All Power Cords
- Can/Crossover Cables
- Agilent Lan Interface Card Built-In
- Solvent Tubing
- Capillaries
- Agilent 4 Peak Test w/ Lab Advisor Diagnostics Report & Mass Spec Tuning Report
- Full 180 Day Parts and Labor Warranty
Agilent 6130A Single Quadrupole Mass Spectrometer Specifications
| Mass Range | 2–3000 m/z |
| Mass Accuracy | ± 0.13 u within the calibrated mass range in scan mode |
| Mass Axis Stability | Mass drift does not exceed the larger absolute value of ± 0.1 u or ± 100 ppm of measured mass over a 12 hour period at constant temperature ± 3 degrees centigrade |
| Scan Speed | 2500 u/s in standard mode, 5250 u/s in fast-scan mode |
| SIM Sensitivity | ESI at 400 µL/min or APCI at 1000 µL/min Selected ion monitoring of m/z 609.3 Positive ionization 6130 and 6140: 1 pg reserpine, 100:1 RMS (20:1 peak-to-peak) |
| Scan Sensitivity | ESI at 400 uL/min or APCI at 1000 μL/min Scan range m/z 100 – 650 Scan speed 2500 u/s Extracted ion at m/z 609.3 Positive ionization 6130 and 6140: 50 pg reserpine, 100:1 RMS (20:1 peak-to-peak) |
| Multisignal acquisition | Ability to cycle through four different acquisition modes on a scan-by-scan basis within a single run |
| Dimensions (W x D x H) | 15 x 29 x 26 in. (38.1 x 73.7 x 66.0 cm) |
| Weight | 110 lb. (50 kg) |
| Electrical Requirements | 200-240 VAC, 50/60Hz |
Agilent 1200 LC System Specifications
| DAD Detector | Specification |
| Detection Type | 1024-element photodiode array |
| Light Source | Deuterium and tungsten lamps |
| Wavelength Range | 190 - 950 nm |
| Short Term Noise (ASTM) Single and Multi-Wavelength | ± 0.8 × 10 -5 AU at 254 and 750 nm |
| Drift | 0.9 × 10 -3 AU/hr at 254 nm |
| Linear Absorbance Range | > 2.0 AU (upper limit) |
| Wavelength Accuracy | ± 1 nm |
| Wavelength Bunching | 1 - 400 nm |
| Slit Width | 1, 2, 4, 8, 16 nm |
| Diode Width | < 1 nm |
| Flow Cells |
Standard: 13 µL volume, 10 mm cell path length and 120 bar (1740 psi) pressure maximum |
| Binary Pump | Specification |
| Hydraulic System | Two dual piston in series pumps with proprietary servo-controlled variable stroke drive, floating piston design and active inlet valve |
| Setable Flow Range | 0.001 – 5 ml/min, in 0.001 ml/min increments |
| Flow Range |
0.1 - 5.0 mL/min |
| Flow Precision | ≤ 0.07% RSD or ≤ 0.02 min SD, whatever is greater |
| Flow Accuracy | ± 1% or 10 µl/min, what ever is greater |
| Pressure Operating Range | Operating range 0 to 600 bar (0 – 7800 psi) up to 5 ml/min |
| Pressure Pulsation | < 2 % amplitude (typically < 1 %), at 1 ml/min isopropanol, at all pressures > 1 MPa |
| Compressibility Compensation | User-selectable, based on mobile phase compressibility |
| Recommended pH Range | 1.0 - 12.5 |
| Gradient Formation | High-pressure binary mixing |
| Delay Volume | 600 to 800 µl, dependent on back pressure |
| Composition Range | 0 to 100% (1 to 99% or 5 µl/min per channel, whatever is greater is recommended) |
| Composition Precision | < 0.15% RSD |
| Composition Accuracy | ± 0.35% absolute |
| Autosampler | Specification |
| Injection Range | 0.1 - 100 µl in 0.1 µl increments |
| Precision |
< 0.25 % RSD of peak areas from 5 to 100 µl < 1 % RSD of peak areas from 1 to 5 µl |
| Pressure Range | Operating range 0 - 60 MPa (0 - 600 bar, 0 - 8850 psi) |
| Sample Viscosity Range | 0.2 to 50 cp |
| Sample Capacity | 100 × 2 mL vials in 1 tray 40 × 2 mL vials in ½ tray 15 × 6 mL vials in ½ tray (Agilent vials only) |
| Injection Cycle Time | 50 s for draw speed 200 µL/min, ejection speed 200 µL/min, injection volume 5 µL |
| Carryover | Typically < 0.1 %, < 0.05 % with external needle cleaning |
| ALS Thermostat | Specification |
| Temperature Range | 4°C to 40°C in 1°C increments |
| Temperature Accuracy at Ambient Temperatures < 25°C and Humidity < 50% | -1°C to +4°C at a setpoint of 4°C |
| Temperature Accuracy at Ambient Temperatures > 25°C and Humidity > 50% | -1°C to +5°C at a setpoint of 4°C |
| Column Compartment | Specification |
| Temperature Range | Ambient -10°C to 80°C at flow rates up to 5 mL/min |
| Temperature Stability | ± 0.15 °C |
| Temperature Accuracy | ± 0.8°C (± 0.5°C with calibration) |
| Column Capacity | Three 30 cm |
| Warm-Up/Cool-Down Time | 5 minutes from ambient to 40°C 10 minutes from 40°C to 20°C |
| Dead Volume |
3 µl left heat exchanger 6 µl right heat exchanger |
| Degasser | Specification |
| Number of Solvent Channels | 4 |
| Maximum Flow Rate | 0 - 10 mL/min per channel |
| Internal Volume Per Channel | Typically 12 ml per channel |
| Materials in Contact with Solvent | PTFE, PEEK |
| pH Range | 1 - 14 |
Computer Specifications |
|
| Processor | Intel Core I5-8500 CPU |
| RAM | 32.0 GB |
| Hard Drive | 500GB Internal SSD |
| Operating System | Windows 11 Professional, 64-bit |
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