Agilent 6140A Single Quadrupole Mass Spectrometer w/ 1200 UPLC
The Agilent 6140A Single Quadrupole Mass Spectrometer w/ 1200 UPLC delivers unmatched analytical performance and proven day-after-day reliability from routine QC to research applications. This 6140A model brings maximum performance plus ultra-fast scanning for fast chromatography and high-throughput applications. This system allows users to rapidly screen compounds and confirm molecular weights, purify target compounds in complex mixtures, quantitate target compounds, positively identify impurities and more. The Agilent 6140A Single Quadrupole Mass Spectrometer provides unmatched sensitivity, simplifying sample preparation and LC method development. An ultrafast scan speed allows users to take full advantage of UPLC separations, as well as featuring ultrafast ion polarity switching to return maximum information from a single injection, even with narrow LC peaks. The Agilent 6140A Single Quadrupole Mass Spectrometer w/ 1200 UPLC can be fully controlled from the included Agilent ChemStation Workstation Software, which allows for user-friendly operation in data acquisition, analysis, instrument control, automation, and more.
Additional high-performance design features of the Agilent 6140A Single Quadrupole Mass Spectrometer include:
- Orthogonal pneumatic nebulizer design allows for a wide range of LC conditions by helping to reduce chemical noise.
- High-capacity solvent drying system – reduces chemical noise and permits the analysis of thermally-sensitive compounds through user control of gas flow rate and gas temperature.
- Dielectric platinum-plated capillary – enhances sensitivity, permits independent optimization of the spray chamber and ion optics, and allows dynamic optimization of in-source fragmentation.
- Fraction collection capability – can monitor and trigger the collection of fractions based on mass, analog signal input, or time. For mass-based determination, up to 16 m/z values can be monitored. Requires optional I/O Accessory Module.
This turnkey Agilent UPLC-MS system was recertified and calibrated by a factory trained engineer and is ready to ship on demand. This system comes with everything needed for easy installation and setup. All of our equipment is fully tested to perform at factory specifications before being shipped.
The Agilent 6140A Single Quadrupole Mass Spectrometer w/ 1200 UPLC includes:
- > Agilent 6140A Single Quadrupole Mass Spectrometer
- > Agilent MS40+ Rotary Vane Vacuum Pump
- > G1312B Binary Pump
- > G1367C HiP Wellplate Autosampler
- > G1316A TCC
- > G1322A Degasser
- > G1315C DAD Detector
- > G1330B ALS Therm
- > Windows 10 Professional 64-Bit Data Station with Flatscreen Monitor
- > ChemStation Version 4.3 Software Installed
- > All Power Cords
- > Can/Crossover Cables
- > Agilent Lan Interface Card Built-In
- > Solvent Tubing
- > Capillaries
- > Agilent 4 Peak Test w/ Lab Advisor Diagnostics Report & Mass Spec Tuning Report
- > Full 180 Day Parts and Labor Warranty
Below is a List of Diagnostic Tests Performed On This System
- Filter Test: The test moves the filter into the light path and measures the relative absorbance in the filter position.
- Dark Current Test: The test measures the dark current from the detector optic.
- Holmium Oxide Test: The test measures the Holmium spectrum from the built-in Holmium filter. The spectrum is evaluated for peaks at different wavelengths.
- Lamp Intensity Test: The test verifies functionality of the UV lamp at various wavelengths.
- Wavelength Intensity Test: The test confirms the accuracy of wavelengths measured.
- Baseline Noise Test: The test measures the amount of baseline noise drift identified by the detector.
- Pressure Test: The pressure test is a quick, built-in test designed to demonstrate the pressure tightness (up to 400 bar) of the system.
- Leak Test: The leak test is a built-in troubleshooting designed to demonstrate the leak-tightness of the pump.
- Thermostat Test: Evaluates the cooling and heating performance of the two Peltier elements.
- Injector Steps: Performs each movement of the sampling sequence under manual control. This is useful for confirming autosampler functionality.
- 4 Peak Test (Isocratic Standard): Standard test published by Agilent to confirm complete functionality of the 1200 UPLC System.
Agilent 6140A Single Quadrupole Mass Spectrometer Specifications
Mass Range
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m/z 10 – 1350
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Mass Accuracy
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± 0.13 u within the calibrated mass range in scan mode
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Mass Axis Stability
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The mass drift does not exceed the larger absolute value of ± 0.1 Da or ± 100 ppm of measured mass over a 12 hour period at constant temperature ± 3 degrees centrigrade.
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Scan Speed
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10,000 u/s in fast mode and 2500 u/s in normal mode
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SIM Sensitivity
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ESI at 400 μ/min or APCI at 1000 μ/min
Selected ion monitoring of m/z 609.3 Positive ionization 1 pg reserpine, 100:1 RMS (20:1 peak-to-peak)
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Scan Sensitivity
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ESI at 400 μ/min or APCI at 1000 μ/min
Scan range m/z 100 – 650 Scan speed 2500 u/s Extracted ion at m/z 609.3 Positive ionization 50 pg reserpine, 100:1 RMS (20:1 peak-to-peak)
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Flow Rate
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ESI: Up to 1.0 ml/min water without a flow splitter
APCI: Up to 1.5 ml/min water without a flow splitter
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Multisignal acquisition
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Ability to cycle through four acquisition modes on a scan-by-scan basis within a single run. Up to four analysis modes can be viewed in the software window and can be linked together to facilitate processing and analysis. Modes of operation: positive/negative polarity switching, variable fragmentor voltage selection, and concurrent SIM/scan.
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Operating Conditions
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Temperature range: 15 °C to 35 °C (59 °F to 95 °F)
Relative humidity: less than 95 % (non-condensing)
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Dimensions
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Height: 65 cm (26 in)
Width: 39 cm (15 in) Depth: 75 cm (29 in) Weight: 50 kg (110 pounds)
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Electrical Requirements
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200-240V, 50/60Hz
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Click Here to View Specifications for the Agilent 1200 UPLC System
Vacuum Degasser
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4 Channels. Up to 10mL/min. pH 1-14
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Binary Pump
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Flow Range: 0.05-5 mL/min Flow Accuracy: +/-1% or 10uL, whatever is greater Operating Pressure: up to 600 bar Compressibility Compensation for smoother output of flow
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HiP Wellplate Autosampler
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Injection Range: 0.1 – 100uL Injection Precision: <1%, 1-5uL; <0.25%, 5-100uL Operating Pressure: up to 600 bar Plate types: over 50 preconfigured plate types available and ability to use customized plates
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Column Compartment
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Temperature Range: 10 degrees C below ambient – 80 C Temp Stability: +/- 0.15 C
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Diode Array Detector
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Data Rate: up to 80Hz Wavelength Range: 190-950 nm Wavelength Accuracy: +/- 1nm Programmable slit width for greater sensitivity or spectral resolution
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Computer Specifications
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Model
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Dell Optiplex 7010 Desktop PC
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Processor
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Intel Core i5-6500 Processor 3.6GHz
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RAM
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16GB
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Hard Drive
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250GB Internal SSD
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Operating System
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Windows 10 Professional, 64bit
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